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Jennifer Hellawell Selected Research

Apelin Receptors

6/2022A Phase I, Open-label, Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of AMG 986 in Healthy Japanese Subjects.
6/2022Evaluation of the Pharmacokinetics and Safety of AMG 986 Tablet and Capsule Formulations in Healthy Adult Subjects: A Phase I, Open-Label, Randomized Study.
4/2022A First-in-Human Study of AMG 986, a Novel Apelin Receptor Agonist, in Healthy Subjects and Heart Failure Patients.
3/2022Effect of Severe Renal Impairment on the Safety, Tolerability, and Pharmacokinetics of AMG 986.

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Jennifer Hellawell Research Topics

Disease

7Heart Failure
06/2022 - 04/2017
1Cardiovascular Diseases (Cardiovascular Disease)
01/2022
1Secondary Hyperparathyroidism
11/2021
1Chronic Renal Insufficiency
11/2021
1Transthyretin-Related Hereditary Amyloidosis
09/2020
1Cardiomyopathies (Cardiomyopathy)
09/2020
1Amyloidosis
09/2020

Drug/Important Bio-Agent (IBA)

4Apelin ReceptorsIBA
06/2022 - 03/2022
1Lipoprotein(a)IBA
01/2022
1Cytochrome P-450 CYP3AIBA
01/2022
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
01/2022
1etelcalcetide hydrochlorideIBA
11/2021
1Proteins (Proteins, Gene)FDA Link
09/2020
1Prealbumin (Transthyretin)IBA
09/2020
1Diflunisal (Dolobid)FDA Link
09/2020

Therapy/Procedure

1Drug Tapering
01/2022
1Renal Dialysis (Hemodialysis)
11/2021
1Therapeutics
04/2017